Biología Computacional

Protein Microarrays in Neurodegenerative Diseases. Current Proteomic Approaches Applied to Brain Function

Pablo San Segundo-Acosta, María Garranzo-Asensio, Ana Montero-Calle, Carmen Oeo-Santos, Mayte Villalba, Ana Guzmán-Aránguez, Rodrigo Barderas. Protein Microarrays in Neurodegenerative Diseases. Current Proteomic Approaches Applied to Brain Function. Neuromethods. Springer. ISBN: 978-1-4939-7118-3. 2017

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The Neuromelanin Paradox and Its Dual Role in Oxidative Stress and Neurodegeneration

Moreno-García A, Kun A, Calero M, Calero O. The Neuromelanin Paradox and Its Dual Role in Oxidative Stress and Neurodegeneration. Antioxidants (Basel). 2021 10(1):124. doi: 10.3390/antiox10010124.

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The specific seroreactivity to ∆Np73 isoforms shows higher diagnostic ability in colorectal cancer patients than the canonical p73 protein

Garranzo-Asensio, M., Guzmán-Aránguez, A., Povés, C. et al, Barderas, R. The specific seroreactivity to ∆Np73 isoforms shows higher diagnostic ability in colorectal cancer patients than the canonical p73 protein. Sci Rep 9, 13547 (2019)

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Identification of novel risk loci and causal insights for sporadic Creutzfeldt-Jakob disease: a genome-wide association study

Jones E, Hummerich H, Viré E, Uphill J, Dimitriadis A, Speedy H, Campbell T, Norsworthy P, Quinn L, Whitfield J, Linehan J, Jaunmuktane Z, Brandner S, Jat P, Nihat A, How Mok T, Ahmed P, Collins S, Stehmann C, Sarros S, Kovacs GG, Geschwind MD, Golubjatnikov A, Frontzek K, Budka H, Aguzzi A, Karamujić-Čomić H, van der Lee SJ, Ibrahim-Verbaas CA, van Duijn CM, Sikorska B, Golanska E, Liberski PP, Calero M, Calero O, Sanchez-Juan P, Salas A, Martinón-Torres F, Bouaziz-Amar E, Haïk S, Laplanche JL, Brandel JP, Amouyel P, Lambert JC, Parchi P, Bartoletti-Stella A, Capellari S, Poleggi A, Ladogana A, Pocchiari M, Aneli S, Matullo G, Knight R, Zafar S, Zerr I, Booth S, Coulthart MB, Jansen GH, Glisic K, Blevins J, Gambetti P, Safar J, Appleby B, Collinge J, Mead S. Identification of novel risk loci and causal insights for sporadic Creutzfeldt-Jakob disease: a genome-wide association study. Lancet Neurol. 2020 19(10):840-848. doi: 10.1016/S1474-4422(20)30273-8.

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Electrochemical immunosensor for IL-13 Receptor α2 determination and discrimination of metastatic colon cancer cells. Biosensors and Bioelectronics

Alejandro Valverde, Eloy Povedano, Víctor Ruiz-Valdepeñas Montiel, Paloma Yáñez-Sedeño, María Garranzo-Asensio, Rodrigo Barderas, Susana Campuzano, José M. Pingarrón. Electrochemical immunosensor for IL-13 Receptor α2 determination and discrimination of metastatic colon cancer cells. Biosensors and Bioelectronics. 2018; 117: 766-772.

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Diagnostic Accuracy of Prion Disease Biomarkers in Iatrogenic Creutzfeldt-Jakob Disease

Llorens F, Villar-Piqué A, Hermann P, Schmitz M, Calero O, Stehmann C, Sarros S, Moda F, Ferrer I, Poleggi A, Pocchiari M, Catania M, Klotz S, O'Regan C, Brett F, Heffernan J, Ladogana A, Collins SJ, Calero M, Kovacs GG, Zerr I. Diagnostic Accuracy of Prion Disease Biomarkers in Iatrogenic Creutzfeldt-Jakob Disease. Biomolecules. 2020 10(2):290. doi: 10.3390/biom10020290.

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Determination of Cadherin-17 in Tumor Tissues of Different Metastatic Grade Using a Single Incubation-Step Amperometric Immunosensor

Alejandro Valverde, Eloy Povedano, Víctor Ruiz-Valdepeñas Montiel, Paloma Yáñez-Sedeño, María Garranzo-Asensio, Nuria Rodríguez, Gemma Domínguez, Rodrigo Barderas, Susana Campuzano, José M. Pingarrón. Determination of Cadherin-17 in Tumor Tissues of Different Metastatic Grade Using a Single Incubation-Step Amperometric Immunosensor. Analytical Chemistry 2018 90 (18), 11161-11167

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An electrochemical immunosensor using gold nanoparticles-PAMAM-nanostructured screen-printed carbon electrodes for tau protein determination in plasma and brain tissues from Alzheimer patients

Razzino CA, Serafín V, Gamella M, Pedrero M, Montero-Calle A, Barderas R, Calero M, Lobo AO, Yáñez-Sedeño P, Campuzano S, Pingarrón JM. An electrochemical immunosensor using gold nanoparticles-PAMAM-nanostructured screen-printed carbon electrodes for tau protein determination in plasma and brain tissues from Alzheimer patients. Biosens Bioelectron. 2020 163:112238. doi: 10.1016/j.bios.2020.

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Investigación